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Figure 3 | EvoDevo

Figure 3

From: Evolution of eye development in the darkness of caves: adaptation, drift, or both?

Figure 3

Embryonic origins of morphological changes in cavefish: loss of eyes and amplification of other neurosensory adaptive structures. Top Drawings in dorsal views of embryos at neural plate stage in surface fish (left) and cavefish (right). Signaling molecules are in red (Hedgehog, Fgf8), the anterior neural plate fated to become the forebrain is grey, the eyefield (i.e., the portion of the neural plate that will give rise to the retina of the eye) is outlined, and the lens placode is blue. Red arrows indicate stimulatory or inhibitory interactions between signaling centers and their modifications in cavefish. The red thunderstorm arrows indicate the negative influence of midline Hedgehog hyper-signaling on the lens. Bottom Drawings in lateral views of the larval head and brain, on which all the known changes in size or number of structures are indicated and compared between surface and cave larvae. tel telencephalon; ob olfactory bulb; hyp hypothalamus.

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